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08/12/2025
In today’s fast-paced urban life, stress takes a toll on the body, accelerating functional decline. With anti-aging becoming a hot topic, NMN supplements have surged in popularity. But how should NMN—a next-generation anti-aging supplement—be taken to truly see results? Many media outlets have analyzed this, and recently healthyd.com featured Life Young Health’s “LIPOSOMAL Extreme Oxygen NMN.” Before purchasing NMN, it’s worth checking out these expert insights.

(Excerpted fromwww.healthyd.com)
NMN is the abbreviation for β-Nicotinamide Mononucleotide, a substance derived from vitamin B3. It naturally exists in human cells and serves as a precursor to NAD+ (Nicotinamide Adenine Dinucleotide), a key molecule that activates longevity-related genes. NMN can be converted into NAD+, which is essential for maintaining normal body functions. In recent years, NMN has been developed into oral supplements and shown to be rapidly absorbed by the human body. Research has found that as we age, the levels of NAD+ in various organs decline, and the body’s ability to produce NAD+ also diminishes. Supplementing with NMN can help repair organs and improve age-related health issues.

The first researcher to discover that NAD+ could reverse aging is Professor David Sinclair, a genetics professor at Harvard Medical School. His research found that oral NMN supplementation can increase NAD+ levels in the body, effectively slowing down the aging process. David Sinclair’s anti-aging research has been published in the prestigious scientific journal《Cell》, and he was named one of the 100 most influential people by 《Time》magazine.

In November 2006, David Sinclair published a study in Nature indicating that administering substances that boost NAD+ levels to mice with a high body fat content (60% fat) could extend lifespan. The study found that mice treated with NAD+-enhancing substances lived on average 15% longer than mice not treated with resveratrol. The research demonstrated that boosting NAD+ in normally fed mice could effectively slow the progression of age-related diseases such as cardiovascular disease, cataracts, and diabetes, although it did not affect overall lifespan.
Multiple studies using mouse models have confirmed that NMN shows significant benefits for individuals with diabetes, Alzheimer’s disease, and ischemic conditions.³
The main benefits of NMN observed from mouse model experiments include:
The NMN oral supplements available on the market often emphasize the following benefits:
NMN is recommended for individuals aged 30–60 years at a total daily dose of 500mg. For those aged 65 and above, a total daily dose of 750mg is considered safe.⁴

A study⁵ tested 10 healthy men who took 100mg, 250mg, and 500mg of NMN. Five hours after ingestion, there were no significant changes in heart rate, blood pressure, blood oxygen levels, or body temperature. Bilirubin levels rose within the normal range, while blood creatinine and blood glucose levels decreased but remained within normal limits./span>
The sleep quality of the 10 men showed no changes. The study found no significant negative effects of NMN in healthy men and confirmed that oral NMN can be used to address age-related health issues.
Another study³ also confirmed that taking 300mg of NMN daily for one year is safe, with no noticeable side effects and no current data suggesting any cancer risk.
|
NMN Brand |
Concentration |
Body Absorption Rate |
Certification |
Origin |
Suggested Retail Price |
|
1. NeoYouth Mirafive NMN 15,000 + 12,000 Ex, The Quintuple Formula |
100% |
Not specified |
GMP, HACCP, COA, Non-GMO, Gluten-Free |
Japan |
[Limited‑time offer] |
|
99.6% |
90% |
GMP, FDA, ISO 9001 |
United States |
HK$2,880 / 60 capsules (1 box) |
|
|
3. CATALO NMN 15000 |
>99% |
Not specified |
Registered with the World Health Organization Tested using High-Performance Liquid Chromatography (HPLC) and certified by third-party organizations/span> |
United States |
HK$3,688 / 120capsules |
|
4. Wright Life NMN15000 |
>99% |
Not specified |
- |
Hong Kong |
HK$1,980 / 60capsules |
|
5. Ensonkan NMN12000+PQQ |
Not specified |
Not specified |
Canada NPN Certified |
Canada |
HK$2,680 / 60capsules |
|
6. Next Miracle Nutrient NMN1500 |
Not specified |
Not specified |
cGMP quality assurance and multiple international certifications |
United States |
HK$2,380 / 60capsules |
|
7. Fine Japan NMN 7500mg |
Not specified |
Not specified |
- |
Japan |
HK$1,700/120capsules |
|
8. Doctor's Choice NMN 16800 |
Not specified |
Not specified |
- |
Hong Kong |
HK$2,799 / 112capsules |
|
9. GNC NMN150000 |
99.5% |
Not specified |
cGMP Quality Assurance |
United States |
HK$1,749 / 60capsules |
|
10. FORCEVAL NMN12000 |
99.9% |
Not specified |
cGMP Quality Assurance |
Not specified |
HK$1,888/120capsules |

The product utilizes Nobel Prize-winning LIPOSOME nanodelivery technology combined with NMN to create “LIPOSOMAL Oxygen NMN,” achieving an absorption rate of up to 90%.
This innovative formula features LIPOSOME nanodelivery technology, with molecules 1,000 times smaller than a human hair, combined with NMN to form “LIPOSOMAL Oxygen NMN.” It effectively protects NMN from stomach acid while allowing it to penetrate cell membranes for superior absorption. Compared to traditional NMN products with less than 10% absorption, the liposomal NMN achieves up to 90% absorption⁶. Paired with the exclusive “2+4 Scientific Formula,” it is ideal for urban adults over 30 who prioritize health.
The exclusive “2+4 Scientific Formula” includes, in addition to LIPOSOME liposomes, 99.6% high-purity β-NMN, significantly higher than the typical <90% purity of conventional NMN products, providing approximately 300 mg per capsule. The formula also includes four active ingredients to enhance the body’s antioxidant capacity and support cellular rejuvenation. The combination of SOD × NMN boosts antioxidant efficacy by 8,000 times⁷, while resveratrol helps activate the longevity gene Sirtuin 1, promoting the conversion of NMN into NAD+. Together with PQQ, Q10, and other synergistic active ingredients, this formula raises NAD+ levels up to six times more than traditional NMN products⁸.

LIPOSOMAL Oxygen NMN features the exclusive “2+4” scientific formula, achieving up to 90% absorption, increasing NAD+ levels sixfold compared to ordinary NMN, and delivering 8,000 times more potent antioxidant effects.
This product not only boosts cellular energy and accelerates metabolism but also strengthens eight major body functions, including repairing bones and joints, slowing eye aging, promoting hair health, supporting brain function, maintaining vascular health, enhancing organ function, aiding weight management, and rejuvenating skin. Users have consistently praised its results. Joanna, a working mother, shared that after giving birth, her memory declined while juggling work and childcare with insufficient sleep. After being introduced to LIPOSOMAL Oxygen NMN, she felt more energetic, her memory noticeably improved, and she now has the mood and stamina to enjoy activities with her children. Similarly, healthcare professional Victoria reported that frequent late-night shifts left her fatigued, but after trying LIPOSOMAL Oxygen NMN — knowing its liposomal formulation ensures higher absorption — she felt more energized, and her skin quality also improved.

The liposomal formulation effectively protects against stomach acid and easily penetrates cell membranes, achieving an absorption rate of up to 90%.
Origin: United States
Recommended Retail Price: HK$2,880 / 60 capsules
>Purchase here<
(The above supplements are not intended for medical use. It is recommended to consult a doctor before consumption.)
To fight aging, besides taking NMN, we can also obtain antioxidant nutrients through daily diet. Consuming the following anti-aging foods can help improve skin quality and offer significant health benefits.
Recommended Anti-Aging Foods
|
Foods |
Benefits |
|
Tomatoes |
Tomatoes are rich in lycopene, vitamins A and C, with antioxidant capacity up to 100 times that of vitamin E. They help the body combat free radicals effectively, slowing down the cellular aging process. |
|
Eggs |
Eggs provide high-quality protein that helps repair skin, while vitamin E offers strong antioxidant effects. Choline, vitamin A, lutein, and zeaxanthin help maintain metabolism and boost immunity. |
|
Carrots |
Carrots contain β-carotene and vitamin A. β-carotene supports antioxidant activity and protects the skin, preventing allergies, while vitamin A helps maintain normal immune function. |
|
Almonds |
Almonds are rich in calcium and vitamin E, aiding scar cell repair and protecting against sun damage. They help eliminate free radicals in the body, keeping cells healthy. |
|
Avocados |
Avocados contain monounsaturated fatty acids, which have been shown to improve the skin’s resistance to UV rays, delay epidermal cell aging, and help reduce “bad” cholesterol levels. |
|
Turmeric |
Turmeric has anti-inflammatory properties and cancer-preventive effects. It improves skin health and combats aging, helping reduce pigmentation or scars caused by aging, hormonal imbalance, or sun exposure. |
|
Broccoli |
Broccoli is packed with antioxidants such as β-carotene, glutathione, and vitamin C. Eating broccoli regularly helps maintain glutathione levels in the body, assisting in the fight against skin aging. |
NMN (β-Nicotinamide Mononucleotide) is a substance derived from vitamin B3. It naturally exists in human cells and is a precursor to the longevity molecule NAD+ (Nicotinamide Adenine Dinucleotide). NMN can be converted into NAD+, which is essential for maintaining normal bodily functions. In recent years, NMN has been developed into an oral supplement and has been shown to be rapidly absorbed by the human body.
Studies have shown that taking 300mg of NMN orally daily for one year is safe, with no significant side effects observed. Currently, there is no evidence suggesting that NMN causes cancer.
NMN is recommended for adults aged 30–60, with a daily total dose of 500mg. For those aged 65 and above, a daily dose of 750mg is still within the safe range.
Reference Source:
1 Mills K ,Yoshida S, Stein L et al. (2016) .Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice[J]. Cell Metabolism, 24(6):795-806.
2 維基百科《大衛·安德魯·辛克萊》
3 The Science Behind NMN–A Stable, Reliable NAD+Activator and Anti-Aging Molecule, National Library of Medicine
4 Taking NMN
5 Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men, National Library of Medicine
6. Liposomes for Enhanced Bioavailablility of Water-Insoluble Drugs: In Vivo Evidence and Recent Approaches. Phamaceutics 2020, 12, 264
7. Capelli 2017. The World’s Strongest and Highest Quality Natural Antioxidant: Astaxanthin. Algae Health Sciences BGG North America
8. Result of Bioavailability Test by Lab
Text: Florence
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